Lenire has been proven safe and effective in large-scale clinical trials involving 600+ patients and with real world patients. Lenire has the most expansive evidence base for a tinnitus treatment device.
Learn About Lenire Clinical Trials.
Bimodal Neuromodulation for Tinnitus in a Clinical Practice Setting: Clinically Significant Benefit for Patients with Moderate or Worse Symptoms:
84.1% of patients with bothersome tinnitus treated at a New York clinic reported clinically significant improvement after treatment with Lenire
Published on: 13/01/2026 Corresponding author: Craig A. Kasper, Juliana M. May, Natalie E. Crossland, and Hubert H. Lim Download.pdf (830.57 KB)
Nature Comms Medicine Publication of Lenire Real World Evidence:
91.5% of 220 real world patients patients had a clinically meaningful reduction in tinnitus in response to treatment with Lenire.
Published on: 28/04/2025 Corresponding author: Emily E. McMahan Au. D., Prof. Hubert Lim Download.pdf (1.10 MB)
Real World Evidence: Lenire & Hearing Aid Users:
Hearing Aid Users Received Additional Benefit in Their Tinnitus Journey with Lenire® Bimodal Neuromodulation Treatment. A retrospective review from Alaska Hearing & Tinnitus Center.
Published on: 28/01/2025 Corresponding author: Dr. Emily E. McMahan Download.pdf (1.79 MB)
Real-World Patient Data: Alaska Hearing & Tinnitus Center:
Effectiveness of bimodal neuromodulation for tinnitus treatment in a real-world clinical setting in United States - A retrospective chart review
Published on: 04/09/2024 Corresponding author: Emily E. McMahan, Hubert Lim Download.pdf (1.34 MB)
TENT-A3 Pivotal Controlled Clinical Trial:
TENT-A3, Neuromod’s third large-scale clinical trial for Lenire, was a controlled trial conducted as part of Lenire’s De Novo submission to the US FDA at three independent sites between March and October 2022 with 112 enrolled participants.
Published on: 19/08/2024 Corresponding author: Michael Boedts, Andreas Buechner, S. Guan Khoo, Welmoed Gjaltema, Frederique Moreels , Anke Lesinski-Schiedat, Philipp Becker, Helen MacMahon, Lieke Vixseboxse , Razieh Taghavi , Hubert H. Lim & Thomas Lenarz Download.pdf (1.32 MB)
TENT-A2 Research Paper:
Different bimodal neuromodulation settings reduce tinnitus symptoms in a large randomized trial
Published on: 30/06/2022 Corresponding author: Hubert Lim Download.pdf (3.97 MB)